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The mammalian body is equipped with various layers of mechanisms that help to defend itself from pathogen invasions. Wild type DC2.
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  • Step 2: Chemotaxis of Phagocytes (for wandering macrophages, neutrophils, and.
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    ) are not disregarded as artifactual vacuolation.

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    Furthermore, the bactericidal function of activated macrophages depends on the presence of peroxynitrite and the fact that inhibition of superoxide or nitric oxide generation inhibits this function [ 54 ].

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    5 micrometers) into membrane-bound vesicles called phagosomes, which are then targeted to the lysosomes for enzymatic.

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  • Figure \(\PageIndex{4}\): Phagocytosis is a multi-step process in which a pathogen is engulfed and digested by immune cells called phagocytes.
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    Phagocytosis is a process by which cells ingest large particles (> 0.

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    Chemotaxis: phagocytes are attracted to microorganisms.